Zidane took charge of his 150th league match as champions Madrid suffered a shock 1-0 loss to newly-promoted Cadiz on Saturday.
Only Miguel Munoz (424) and Vicente Del Bosque (153) have overseen more LaLiga matches whilst at the helm of Madrid.
Zidane, who made his coaching debut in his first spell at the Santiago Bernabeu in 2016, guided Los Blancos to LaLiga glory last season.
The Frenchman has tallied 102 LaLiga victories, only behind Miguel Munoz (257).
In two spells with Madrid, former star Zidane has won three Champions League titles, two LaLiga trophies, two Club World Cups, two UEFA Super Cups and two Supercopa de Espana crowns.
Madrid remain top of the table in 2020-21, ahead of Getafe, Cadiz and Granada on goal difference.