Talleres de Córdoba hosted São Paulo in the First Round of the Group Stage of the 2024 Copa Libertadores. Talleres started the phase on the right foot and defeated their opponent 2-1.

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The home team opened the scoring with a goal from Ramiro Ruiz in the 45th minute of extra time, a lead that would be extended in the 53rd minute with a goal from Ruben Botta. Luciano pulled one back for São Paulo in the 67th minute, but it wasn't enough as Talleres secured their first three points.