All sporting activity in Italy has been suspended until April 3 by the Italian National Olympic Committee (CONI) due to the coronavirus spread, with football set to be the most-impacted sport.
The CONI announcement on Monday confirmed a suspension, subject to government ratification, that many had expected.
Italy has been one of the worst affected countries by the outbreak of the disease, with approximately 16 million people quarantined in order to halt the spread of the disease.
A government decree had already confirmed there were to be no spectators at any sporting events until April 3, but the latest announcement followed a significant increase in coronavirus cases, with 7,375 Italians having been infected.
After weeks of uncertainty and postponed fixtures, Serie A returned to action last weekend with five games played behind closed doors. Twelve rounds remain of the 2019-20 season, with Juventus topping the standings with a one-point lead over second-place Lazio.
Monday's announcement from the Italian Olympic Committee, which is known as CONI, came minutes before Sassuolo was to host Brescia in a soccer match - the match began as scheduled.
Serie A has not been canceled since World War II.
CONI's decision does not include international competitions scheduled to be played in Italy, as the governing body has no jurisdiction over those. Juventus and Atalanta will still host their Champions League last-16 second leg ties against Lyon and Valencia, respectively, while Inter and Roma are still set to face Getafe and Seville in the Europa League as scheduled.
Events around the world have been affected by the spreading virus, including UEFA Champions League soccer matches, Japan's professional baseball season and the Indian Wells tennis tournament.
Following Monday's news, here are the biggest clubs' Serie A and Coppa Italia matches set to be affected:
Juventus:
Bologna v Juventus, March 13
Juventus v Lecce, March 21
Juventus v Milan (Coppa Italia semi-final second leg), TBC
Lazio:
Atalanta v Lazio, March 15
Lazio v Fiorentina, March 20
Inter:
Inter v Sassuolo, March 15
Parma v Inter, March 22
Napoli v Inter (Coppa Italia semi-final second leg), TBC
Milan:
Lecce v Milan, March 15
Milan v Roma, March 22
Juventus v Milan (Coppa Italia semi-final second leg), TBC
With no matches set to take place until April 3, a deadline that could feasibly be pushed back even further, teams will resume the Serie A season with between 12 and 14 matches still to play.
With Euro 2020 set to begin on June 12, it leaves just 70 days between the two key dates, though facilities will have to be handed over to UEFA well before the tournament's kick-off.
If Champions League and Europa League matches continue to go ahead as planned, some Italian teams could have many as 20 matches across all competitions to cram into their schedules.