Denver Broncos quarterback Peyton Manning labelled drug use allegations as "complete garbage".

An Al Jazeera documentary set to air on Sunday alleges human growth hormone (HGH) was mailed to Manning's wife after he underwent neck surgery in 2011, according to The Huffington Post.

In a statement, Manning rubbished the reports.

"The allegation that I would do something like that is complete garbage and is totally made up," Manning said, via the Denver Post.

"It never happened. Never. I really can't believe somebody would put something like this on the air. Whoever said this is making stuff up."