Serena Williams has announced she will not take part in the tennis tournament at the Tokyo Olympics.

Rafael Nadal and Dominic Thiem have already opted out of featuring at the Games next month, with Roger Federer and Novak Djokovic yet to commit.

Williams, who made her Olympics debut in 2000 and has four gold medals, is now atop the list of big-name absentees, having previously expressed reservations because she would not be able to take her three-year-old daughter Olympia along with her.

"I'm actually not on the Olympic list – not that I'm aware of. If so, then I shouldn’t be on it," she said at a pre-Wimbledon news conference.

"There's a lot of reasons that I made my Olympic decision. I don’t feel like going into them today. Maybe another day. Sorry."

Williams will begin her pursuit of an eighth Wimbledon and 24th grand slam singles title against Aliaksandra Sasnovich on Tuesday.