All three players have been left out of the 18-man squad for the clash with Abelardo's side.
The Derby Squad— FC Barcelona (@FCBarcelona) January 4, 2020
2. N. Semedo
4. I. Rakitic
18. Jordi Alba
20. S. Roberto
21. F. de Jong
26. Iñaki Peña
27. C. Pérez
31. Ansu Fati
Head coach Ernesto Valverde confirmed earlier on Friday that goalkeeper Ter Stegen would be unavailable due to a knee tendon injury that also makes him a doubt for the Supercopa de Espana in Saudi Arabia.
Midfielder Arthur is expected to be out for three weeks with a groin problem, while forward Dembele has not yet recovered from his latest thigh muscle injury.
There is also no room in the squad for defender Jean-Clair Todibo, who has been linked with moves to Milan and Everton this month.
The good news for Barca is that Ansu Fati has been given the all-clear to travel, while Lionel Messi, Luis Suarez and Arturo Vidal - who only trained for the first time since the holidays on Thursday - are included.
Barca head into 2020 with a two-point lead at the top of LaLiga.