Brazil made it six wins from six games in World Cup qualifying after Neymar's goal and Lucas Paqueta's late strike secured a 2-0 win over Paraguay.
Neymar broke the deadlock in the fourth minute before substitute Paqueta completed the scoring in the third minute of stoppage time as Brazil preserved their 100 per cent record in CONMEBOL qualifying on Tuesday.
A 67th international goal for Neymar – only 10 adrift of all-time record holder Pele – helped send Brazil six points clear of rivals Argentina atop the standings on the road to Qatar 2022.
Brazil entered the contest away to Paraguay amid continued uncertainty over the scheduled Copa America and their participation, with the Selecao squad united in their opposition of hosting the showpiece tournament on home soil.
On the field, Tite's Brazil impressed and quickly stamped their authority on the match thanks to star Neymar in Asuncion.
Neymar put Brazil ahead with a simple side-footed finish in the fourth minute after Richarlison scuppered his attempt to volley Gabriel Jesus' cross.
It was a good omen for Brazil, with the Copa America champions winning all eight of their previous games in which the Paris Saint-Germain forward had scored in World Cup qualifiers.
A ferocious long-range strike from Paraguay defender Omar Alderete almost restored parity four minutes later but Brazil goalkeeper Ederson was forced into a stunning save.
Richarlison, who almost added a second goal in the 12th minute, put the ball in the back of the net with a brilliant half-volley in the second minute of stoppage time but it was ruled out for offside.
The tempo dropped in the second half however Marquinhos went close to doubling Brazil's lead, with his header sailing just wide of the post in the 55th minute.
Richarlison was in the thick of the action with 20 minutes remaining following a dazzling run into the box however he was thwarted by Paraguay, but Paqueta struck in the 93rd minute to make sure of the points.
What does it mean? All eyes on Copa America
After extending their winning streak to seven matches, attention will now shift to the scheduled Copa America. It remains to be seen whether Tite's men will take part, with the event set to start on Sunday.
Clean sheet specialists
Amid their winning run, Brazil – who have not lost since their 1-0 friendly defeat to Argentina in 2019 – have only conceded two goals, keeping six clean sheets in the process.
While Paraguay only lost by one goal, they never really troubled Brazil. Eduardo Berizzo's men have now gone four matches without a win, claiming just one victory from their six qualifiers to date.
Brazil are scheduled to face Venezuela in the Copa America curtain-raiser on Sunday, while Paraguay are due to meet Bolivia on Monday.