The United States will renew their rivalry with Canada in the inaugural CONCACAF Nations League, while Mexico will come up against Panama.
Similar to UEFA's Nations League, the North American competition has been created to maximise the quality, quantity and frequency of competitive matches for all of CONCACAF's 41-member associations.
Draw Delivers Groups for the Inaugural Edition of the Concacaf Nations League #CNL— Concacaf Nations League (@CNationsLeague) March 28, 2019
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Sorteo Revela Grupos para la Edición Inaugural de la Liga de Naciones Concacaf
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The draw took place in Las Vegas on Wednesday, with Gregg Berhalter's unbeaten USA drawn alongside Canada and Cuba in Group A of League A.
Gerardo Martino's Mexico – who have won their opening two games under the former Barcelona and Argentina head coach – will face Panama and Bermuda in Group B.
Adopting a round-robin, home-and-away format for the group phase – taking place in September, October and November this year – the four group winners from the top tier will advance to the final championship.
The semi-final and final will be played in March 2020, while the bottom teams from League A and B will be relegated as the League B and C winners gain promotion.
CONCACAF president Victor Montagliani said: "Through the Nations League, we have opened the doors of CONCACAF, and its football, to all."
Group A: USA, Canada, Cuba
Group B: Mexico, Panama, Bermuda
Group C: Honduras, Trinidad and Tobago, Martinique
Group D: Costa Rica, Haiti, Curacao
Group A: French Guiana, St Kitts and Nevis, Belize, Grenada
Group B: El Salvador, Dominican Republic, St Lucia, Montserrat
Group C: Jamaica, Guyana, Antigua and Barbuda, Aruba
Group D: Nicaragua, Suriname, St Vincent and the Grenadines, Dominica
Group A: Barbados, Cayman Islands, Saint Martin, U.S. Virgin Islands
Group B: Bonaire, Bahamas, British Virgin Islands
Group C: Guatemala, Puerto Rico, Anguilla
Group D: Guadeloupe, Turks and Caicos Islands, Sint Maarten