Kuyt gets the better of Liverpool in UCL boil-over
Vedat Muriqi's maiden Champions League goal saw Fenerbahce, which twice came from behind, beat Liverpool 3-2.
Fener went into the match contest at Sukru Saracoglu Stadium without a win to its name in this season's competition.
Yet against his former club, Fener interim coach Dirk Kuyt masterminded a surprise victory, with substitute Muriqi the host's hero with a 79th-minute header.
Liverpool set the tone by having four shots in the opening five minutes, which is the first time it has managed such a feat in a Champions League match since March 2009, though it was perhaps fortunate not to concede a penalty when Kostas Tsimikas put both hands in the back of Mason Greenwood in the Reds' area.
Fener's frustration was swiftly compounded when Trey Nyoni volleyed in, becoming the youngest player in Liverpool's history to score his first goal for the Reds in a European Cup/Champions League match.
Irfan Can Kahveci prodded Archie Brown's centre against the crossbar from point-blank range as Fener sought an instant response.
But Kuyt's team had its equaliser in the 29th minute, with Greenwood's free-kick taking a big deflection off Jeremy Jacquet in the Liverpool wall and leaving Alisson flat-footed.
Liverpool came out strong in the second half, but it was not until Andoni Iraola turned to his bench that it made another breakthrough.
Cody Gakpo crossed in for his fellow substitute Alexander Isak to head home in the 69th minute.
Yet four minutes later, Alisson was caught out from a well-worked Fener corner, with Gakpo only able to flick the ball on for Brown, who nudged in at the back post.
Six minutes later, Fener had swung the tide completely. Three Liverpool players failed to deal with a looping cross, and with Alisson stuck on his line, Muriqi sent a brilliant header into the left-hand corner.
Ederson had to deny Virgil van Dijk once more, and Gakpo tried his luck from range, but Liverpool slipped to its first Champions League loss of the season.
