Maurizio Sarri claims he is pondering playing the Juventus Under-23 team against Roma this weekend because of the toll a hectic Serie A schedule has taken on his squad.

Juve was crowned Serie A champions for a ninth successive season when it beat Sampdoria 2-0, but a much-changed XI went down by the same scoreline at Cagliari three days later.

Six days after the conclusion of its domestic season on Sunday (AEST), Sarri's men must try to overturn a 1-0 last-16 deficit against Lyon in the Champions League.

"The problem is that that we are the only team in Europe who will have to play five times in 12 days," Sarri said. "We'll see how we are tomorrow [Thursday] and whether we ought to field the Under-23 team in its entirety at the weekend, so that everyone can get a bit of rest.

"We had nine players left at home with injuries today, so obviously I've got some doubts ahead of Lyon. We’ll have to see who recovers."

One player not spared 90 minutes in Sardinia was Cristiano Ronaldo, who toiled in vain as he tried to close the four-goal gap Lazio's Ciro Immobile has opened up at the top of the Capocannoniere standings.

"Speaking to him yesterday [Tuesday], he was very motivated, wanted to play, was really enthusiastic and felt good," Sarri said. "We made the decision together, he knows his body better than anyone."