Scott Parker's side got that sinking feeling at Craven Cottage, where first-half goals from Ashley Westwood and the in-form Chris Wood – his 50th for the club – consigned the club to an immediate return to the Championship.

It is the first time in Premier League history that all relegation slots have been confirmed with as many as three matches remaining.

Matej Vydra set Westwood up for the opener after 35 minutes and Wood clinically fired home his eighth goal in as many games to leave Fulham shellshocked just before the break.

The Cottagers have picked up only one point from seven games since a surprise 1-0 victory at Liverpool in March.

The London club's fate was confirmed with three games to play, as they are 10 points behind Southampton and Brighton and Hove Albion.

Burnley was able to celebrate retaining their top-flight status after marking Sean Dyche's 350th league game in charge of the club by securing three precious points.

Fulham goes down along with rock bottom Sheffield United and West Brom, which was sent down with a 3-1 loss at Arsenal on Monday (AEST).

The Cottagers, who have won just five matches, are the 17th club to go straight back down having won the Championship play-offs the season before.