The 18-year-old scored three goals and registered two assists in three league games last month, helping Leverkusen to second in the table - behind Bayern Munich only on goal difference.
Wirtz has already managed four goals and leads the Bundesliga charts for assist (five) in just six appearances. In total, the versatile attacker has been involved in a goal every 47 minutes across all competitions, the best minutes per goal involvement ratio of all players in Europe's top five leagues to play at least 500 minutes.
The attacking midfielder's winner against Mainz also made him the youngest player to reach double figures for goals in the German top-flight, doing so at 208 days younger than Lukas Podolski (18 years, 353 days for Cologne in 2004).
Leverkusen sporting director and former midfielder Simon Rolfes praised the teenager's talent and willingness to better himself, comparing him to Kai Havertz, who was sold to Chelsea in 2020 after a similarly meteoric rise.
"The attitude is very good," Rolfes said. "With players and we could see it with Kai Havertz, they know their quality. They are 18 and self-confident because they know about their quality.
"Special players have that – they can feel that, feel it directly on the pitch. Playing with other good players, they're able to handle it and adapt to the different speed of the game.
"He will improve year by year. Although he already has a high level. His biggest strength and you could see that in all the years in the youth team, is that he gives his best in each game.
"Doesn't matter where he was playing or which team-mates he was playing with. The first team, U19, U13 etc, he was always giving his best. That is a key element in his development that he is able to adapt at higher levels but he has the ambition to always improve and you have to improve."
Leverkusen captain and first-choice goalkeeper Lukas Hradecky, 31, echoed Rolfes' sentiments as he hailed the work of the youngster following his individual accolade.
"Florian is a great player," Hradecky said to the Bundesliga's official website. "He’s doing an outstanding job and works hard on himself."
Wirtz will be hoping to maintain his streak of scoring or assisting in every Bundesliga appearance so far this season as Leverkusen host league leaders Bayern on October 17.