Barcelona travel to fellow heavyweights Juventus in the pick of the second round of Champions League group-stage fixtures on Wednesday.

Cristiano Ronaldo will not get the chance to resume his rivalry with Lionel Messi after contracting coronavirus, but a number of other superstars will be on the field at Allianz Stadium.

Juve and Barca picked up victories in their opening games and that was also the case for Manchester United, who triumphed away at Paris Saint-Germain and now welcome RB Leipzig to Old Trafford.

PSG head to Turkey for their first competitive meeting with Istanbul Basaksehir while Chelsea, held by Europa League champions Sevilla in their first game, face a potentially tricky trip of their own at competition debutants Krasnodar.

Here is some of the key Opta data from day two of matchday two.

Juventus v Barcelona: Milestone victory in sight for Juve

Juventus' tally of six home games without losing to Barcelona is their joint-best total against any team in European competition, alongside another LaLiga side in Atletico Madrid.

Barca are unbeaten in six games against Italian opposition in the Champions League, however, and have only suffered defeat once in their last 17 away games in the competition.

Should Juve come out on top in Turin, it will be their landmark 100th victory in UEFA's showpiece competition in what will be their 200th game.

Krasnodar v Chelsea: Blues target first win

After drawing 0-0 with Sevilla in their opener, Chelsea are looking to avoid going back-to-back games without a win to begin a Champions League campaign since the 1999-2000 season.

The London club have lost only one of their last 11 away games in European competition, though that came in their last outing - a 4-1 loss to Bayern Munich.

None of the previous six Russian sides to have competed in the Champions League have won their first home game, which Krasnodar will be looking to put right on Wednesday.

Manchester United v RB Leipzig: More German joy for Red Devils?

United have gone 10 home games without being beaten by German opposition in European competition since a 1-0 loss against Bayern Munich in 2001, winning seven of those.

However, the Red Devils have lost four of their last six Champions League matches at Old Trafford - as many as in their previous 71 games combined.

Leipzig beat Tottenham home and away last season - their only previous encounters with an English team - and are unbeaten in five away games in the competition.

Istanbul Basaksehir v Paris Saint-Germain: Away-day specialist Mbappe

Basaksehir have won three of their last four home matches in European competition but this will be the first occasion they have hosted Champions League football.

On the back of their loss to United last week, PSG are out to avoid successive defeats to begin a group campaign for the first time since the 2004-05 campaign.

Kylian Mbappe played a key part in his side's run to the final last term and has been directly involved in 20 goals in his 16 away Champions League appearances. He has registered at least one goal or assist in 13 of those 16 away appearances.

Other fixtures:

Sevilla v Rennes:

12 - Sevilla are unbeaten in 12 home games in European competition since a 2-1 Champions League defeat to Bayern Munich in April 2018.

2 - Only two of the 10 previous French sides to have played in the Champions League have won their first ever away match - PSG and Auxerre in 1994 and 1996 respectively.

Borussia Dortmund v Zenit:

6 - Zenit are winless in their last six European matches against teams from Germany, stretching back to a 2-1 victory against this week's opponents Dortmund in March 2014.

3 - Dortmund have won three Champions League home games in a row and are looking to make it four on the spin for the first time since a run of seven between September 2012 and October 2013.

Club Brugge v Lazio:

4 - Brugge have scored only four goals in their last 12 matches with Italian opposition and are winless in their last nine meetings with clubs from the Peninsula.

5 - Lazio have lost their last five away games on the continent, all of which came in the Europa League in the 2018-19 and 2019-20 seasons.

Ferencvaros v Dynamo Kiev:

3 - Dynamo have won just three of their last 24 away games in the Champions League, drawing three of their last four.

24 - Ferencvaros kept a clean sheet in their first home game in the competition but have since shipped 24 goals across their last six matches, giving them the highest goals-conceded-per-game ratio of any team to have played in more than one campaign.