Alize Cornet's preparations for Wimbledon suffered another blow on Sunday as the Frenchwoman slumped to a surprise first-round defeat against Alison Riske at the Aegon International.
World number 24 Cornet, who beat Serena Williams on her way to the fourth round at the All England Club in 2014, succumbed to a 6-0 6-3 loss in Eastbourne.
Cornet - beaten in the first round of the Aegon Classic earlier this week by another American, Christina McHale - struggled on her serve throughout and found Riske in clinical form as she bageled her opponent in the first, before then breaking in the first game of the second.
Although Riske failed to consolidate that break, Cornet ended a match in which she won just 19 of 49 service points by being broken twice more as her brief resistance wilted.
Riske's compatriot Sloane Stephens survived a scare, coming back from a set down to beat British wildcard Naomi Broady 3-6 6-3 7-6 (7-4).
Stephens squandered two match points as Broady broke to put the deciding set back on serve after falling 4-1 behind, however, the American then took control of the subsequent tie-break and wrapped things up to progress to the second round.
There were no such problems for world number 31 Belinda Bencic, the 18-year-old beating Mona Barthel 6-4 7-6 (9-7).
Caroline Garcia needed just over an hour to see off Roberta Vinci 6-2 6-2 and Casey Dellacqua overcame Anna Schmiedlova 6-2 6-4, but world number 34 Zarina Diyas suffered a 6-3 6-2 loss to wildcard Johanna Konta.
In the day's other first-round match, Coco Vandeweghe was a 6-7 (3-7) 6-1 6-1 winner over Johanna Larsson.