Inter have confirmed that five members of staff have tested positive for coronavirus.
Managing directors Alessandro Antonello and Giuseppe Marotta, sporting director Piero Ausilio and lawyer Angelo Capellini have all returned positive tests.
An unspecified member of the Serie A leaders' technical staff has also tested positive for COVID-19.
A statement on Inter's official website read: "All coaches and the entire team will follow the procedures set out in the health protocol."
Inter will be desperate to ensure that this outbreak does not spread to their first-team squad or coaches.
The Italians extended their lead at the summit of table to four points with a 3-0 win over city rivals Milan last time out.
With no European commitments over the remainder of the season, Antonio Conte's men are strong favourites to end an 11-year wait for the title.
They last lifted the Scudetto during Jose Mourinho's spell at the club in 2010, which also brought European Cup success.
Juventus, who have won the last nine Serie A titles, sit eight points back in third place with a game in hand.
Inter are next in action on Sunday, when they face Genoa at the San Siro.