Liverpool have been handed a boost by the return of Joel Matip for their meeting with Burnley, but Mohamed Salah and Roberto Firmino must settle for a place on the bench.
A run of four Premier League games without a win has seen the Reds drop down to fourth, six points behind leaders Manchester United, ahead of Thursday's clash at Anfield.
Jurgen Klopp's side have scored just once in that run and have not managed a goal in any of their last three outings.
Their talisman Salah has summed up their struggles, with the Egypt star having failed to score in any of his last four league appearances – his current drought lasting 365 minutes.
Only once has Salah gone longer without a goal for Liverpool and the 28-year-old has been rotated out by Klopp, alongside fellow forward Firmino.
Since Salah joined Liverpool in 2017, they have won four of their five Premier League games when both he and Firmino have been absent from the starting XI, including two wins over Burnley.
Sadio Mane is the only member of Liverpool's first-choice front three to start, with Divock Origi and Xherdan Shaqiri named alongside the Senegal forward.
Along with Firmino, Mane has netted four times in his last four league appearances against Burnley.
Further back, Jordan Henderson misses out through what Liverpool described as a "minor fitness issue", with Georginio Wijnaldum named as captain.
Under Klopp, Liverpool's league win rate without Henderson featuring is 56 per cent, down from 66 when the England international plays.
The main positive for the Reds comes at the back, with Matip – who went off injured in a 1-1 draw with West Brom on December 27 – joining Fabinho in the centre of defence.
Matip and Fabinho will be up against Ashley Barnes and Chris Wood, who has only played more games (seven) and minutes (435) against Southampton without scoring in the Premier League than he has against Liverpool (six games, 400 minutes).
Indeed, Burnley have failed to score in six of their last seven away Premier League fixtures, with their only goal in this run an own goal from Arsenal's Pierre-Emerick Aubameyang, and the Clarets have lost their last two matches.