The second week of the NFL season gave us what Week 1 could not – fewer injuries and more close finishes.

The fourth quarter was crucial on Sunday as several high-profile games gave us nail-biting endings. Gardner Minshew could not quite get the Jacksonville Jaguars past the Houston Texans as he made his first career start in place of injured quarterback Nick Foles, while the Indianapolis Colts' defense helped Jacoby Brissett claim his first win of the season since Andrew Luck retired.

But setbacks were not inescapable after the Pittsburgh Steelers were plagued by injuries in their home opener against the Seattle Seahawks. The Steelers fought down to the final fourth-and-one wire of a game that had four sacks and four first downs over the first five possessions alone, but the Seahawks picked up their eight win in the team's last nine games.

Other games were not as competitive, like the New England Patriots' 43-0 shutout of the Miami Dolphins and the San Francisco 49ers' 41-17 rout of the Cincinnati Bengals.

Then there are the Buffalo Bills, who moved to an unlikely 2-0 after they spoiled the New York Giants' home opener 28-14, while head coach Matt LaFleur recorded his first win at Green Bay as the Packers beat the Minnesota Vikings 21-16 for the first time since 2016.

Injury report

Steelers quarterback Ben Roethlisberger was seen shaking his throwing arm at various points in the first half against the Seahawks and even exited to the locker room before returning to the sideline to play through the injury. He was later ruled questionable to return to start the second half but never made it back after being replaced by backup Mason Rudolph.

Meanwhile, Steelers team-mate and running back James Conner was also questionable to return with a knee injury suffered in the second half. The Steelers also lost linebacker Vince Williams and safety Sean Davis to injuries.

49ers tackle Joe Staley was carted off the field against the Bengals with a leg injury and did not return. Niners coach Kyle Shanahan revealed after the game that Staley suffered a broken fibula.

Washington Redskins tight end Vernon Davis, starting in place of Jordan Reed as he recovers from a concussion, sustained an eye injury against the Dallas Cowboys.

Another less injury-prone quarterback went down as New Orlenas Saints veteran Drew Brees injured his throwing hand making contact with Los Angeles Rams defensive tackle Aaron Donald in their NFC title rematch. He was sidelined with his thumb taped as Teddy Bridgewater took over under centre.

By the numbers

After being a healthy scratch in Week 1, Redskins running back Adrian Peterson scored his 107th career rushing touchdown to pass Hall of Famer Jim Brown on the all-time list. He is three rushing touchdowns behind Walter Payton for fourth in NFL history.

Cowboys tight end Jason Witten is back in a big way, as the veteran scored in back-to-back weeks for the first time since Weeks 12 and 13 of the 2017 season.

Antonio Brown's touchdown catch during his Patriots debut against the Dolphins made him the 72nd player to catch a regular-season touchdown pass from Tom Brady, which extends a league record for the 42-year-old New England quarterback.

Rookie sensation and Arizona Cardinals QB Kyler Murray joined Carolina Panthers veteran Cam Newton as the only players in NFL history to throw for more than 300 yards in their first two starts.

Steelers receiver JuJu Smith-Schuster hit 2,500 career receiving yards against the Seahawks, becoming the youngest player in league history to accomplish the feat.

It was a good day for fantasy owners with New England's defense after the Patriots shut out the Dolphins.

Kansas City Chiefs quarterback Patrick Mahomes exploded in the first half against the Oakland Raiders, with his four touchdown passes and 313 yards helping him become the first signal-caller to throw for more than 278 yards in any quarter since Brees did so in 2008.

Quotables

Giants coach Pat Shurmur on replacing Eli Manning with Daniel Jones: "I think we have to look at how our team played and we have to go back and take steps to get better in all areas. I don't think that's a conversation for right now. Everybody has to play better."

Patriots coach Bill Belichick on having Brady throw deep despite being up 37 points: "We're playing 60 minutes. You've got to play 60 minutes."

Week 1 NFL scores

Thursday's game

Buccaneers 20, Panthers 14

Sunday's games

Ravens 23, Cardinals 17
Lions 13, Chargers 10
Colts 19, Titans 17
49ers 41, Bengals 17
Texans 13, Jaguars 12
Packers 21, Vikings 16
Cowboys 31, Redskins 21
Seahawks 28, Steelers 26
Bills 28, Giants 14
Patriots 43, Dolphins 0
Chiefs 28, Raiders 10
Rams 27, Saints 9
Bears 16, Broncos 14