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Murray, a five-time finalist in Melbourne, went into isolation at home after returning a positive test on 14 January.

The three-time Major winner, currently ranked No.123 in the world, had hoped to compete at the first grand slam of the year after being granted a wildcard.

However, tournament organisers indicated it would be difficult for Murray to remain in the draw as he would be unable to travel via one of the official charter flights containing other players before going through the required period of quarantine.

On Saturday (AEDT) the 33-year-old confirmed he had been unable to come to a "workable" solution with authorities.

In a statement carried by The Guardian and other UK media outlets, Murray said: "Gutted to share that I won't be flying out to Australia to compete at the Australian Open.

"We've been in constant dialogue with Tennis Australia to try and find a solution but we couldn't make it work.

"I want to thank everyone there for their efforts, I'm devastated not to be playing out in Australia. It's a country and tournament that I love."

The build-up to this year's Australian Open has been impacted by players having to spend a two-week quarantine in their hotel accommodation.

A total of 72 competitors have been unable to leave their rooms after positive coronavirus tests among passengers on the chartered flights to Melbourne.

Players have been unable to access practice courts and many have complained on social media about sub-standard food and conditions, with Yulia Putintseva, the world No.28, sharing videos showing mice in her room.

The tournament is due to start on 8 February.