Medvedev advanced to the quarter-finals with a comfortable 6-3 6-4 6-3 victory over 24th seed Dan Evans in New York.

US Open finalist in 2019 and Australian Open runner-up this year, Russian star Medvedev is yet to drop a set at Flushing Meadows this week.

As Dutch qualifier Botic Van De Zandschulp awaits, Medvedev discussed expectations at the US Open in pursuit of his first major title.

"I always say I take it match by match," Medvedev told reporters after hitting 42 winners in one hour, 43 minutes. "You can lose first round, you can lose final. If I play good, I know what I'm capable of. It's tough to beat me.

"In Wimbledon, I was honest, I lost against a great player, Hubert is playing great. I think he's on the rise. He's going to be even better ranked and maybe he's gonna go further in slams. He beat Roger [Federer] after me.

"But again, I was not talking about match itself where the loss was okay, I would say. I was talking about the result in general, and fourth round is not enough for number two in the world, especially I like grass more than clay, so maybe on clay I would not say this.

"Yeah, it's the same every tournament. If you're top seed, if you are not in the final, let's say Cincinnati, I lost against Rublev, brutal match, really strong play from him. But if you talk about the result itself, semi-final was not good enough.

"There is not much to add. I want to win every tournament I play in, without putting pressure on myself. Because again, I know how to win matches, and I know sometimes why I lose them, so that's just learning and being better for the next time."

Medvedev is 31-5 on hard courts in 2021 and 162-61 in his career, while he has won 11 of his 12 ATP titles on hard courts.

The 25 year-old owns a 17-4 record (80.95 per cent) at the US Open – his most wins and highest win percentage at a grand slam event.

"Feeling great before the second week," Medvedev said. "Feeling great with my tennis, my mental, my physical. Just looking forward."

Medvedev, who lost a thrilling US Open final to Rafael Nadal two years ago, added: "Now I just want to make it to the finals again to have another thing to remember and hopefully a better one."