Tottenham confirmed that Ventrone, who joined the club last November as part of Antonio Conte's backroom staff, had passed away.

Ventrone was nicknamed 'The Marine' because of his tough training sessions, yet he was well respected by Tottenham's players.

Kane was among those to pay tribute to Ventrone on social media, saying he will forever be grateful for the advice received from the Italian.

"A truly remarkable man. I'm devastated by the passing of our coach Gian Piero," Kane posted. "My love and strength is with his family at this time. 

"His words and wisdom will live on with me for the rest of my life and I'm just grateful I had the opportunity to spend time with him. RIP Prof."

Italian newspaper Gazzetta dello Sport reported that Ventrone died on Friday (AEDT) in Naples at the age of 62 after a battle with leukaemia.

Ventrone spent a decade at Juventus and also worked for Catania, JS Suning, GZ Evergrande and Ajaccio, prior to reuniting with Conte in north London.

He was credited with helping to drive a radical improvement in the Tottenham players' fitness, with forward Richarlison among those to benefit.

"Since I arrived at Tottenham, Gian has been a huge inspiration to me," the Brazil international said. "He always said that I would help him a lot during the season.

"But who helped me was him... much more than he can imagine. Today we woke up to the terrible news of his passing and we are all devastated.

"We will continue to play for you, my friend, who taught us to never give up! Thank you so much and rest in peace!"

Ventrone had two stints at Juventus between 1996 and 1999 and 2001 and 2004, helping to shape the side that won the Champions League in the first of those spells.

The Italian giant paid tribute in a statement on its official website.

"We will always remember his attention to detail, his work philosophy, and perhaps his greatest talent, the understanding that football – and especially the fundamental components of conditioning and athleticism – was gradually entering a new era," the statement read.

"A new era that, in part, he helped write."