Barca finds itself in difficult financial circumstances, with six-time Ballon d'Or winner Lionel Messi forced to join Paris Saint-Germain on a free transfer after the Blaugrana were unable to provide him with a new contract.
The Blaugrana have won just one trophy – a Copa del Rey – in the last two seasons and have not started their first campaign without Messi in 16 years well, sitting bottom of their Champions League group and winning just three of their first seven LaLiga games.
Jose Enrique believes the dramatic decline of a once-formidable club is down to a string of poor decisions from the hierarchy and points the finger primarily at Rosell, who served as Barca president from 2010 to 2014.
"Well, I think, with a completely open heart and honestly, I think Sandro Rosell has just destroyed this club," Jose Enrique told Stats Perform.
"It is destroyed, economy-wise. [New Barca president Joan] Laporta is obviously taking everything now because obviously, it's anyone and everyone asking him for answers. But it's true that he arrives to a club that is very, very in debt with a lot of players on a lot of money."
The one-time Liverpool and Newcastle United defender was particularly scathing about Barca's activity in the transfer market over the last few years under the presidency of Josep Maria Bartomeu, who replaced Rosell in 2014 before stepping down in 2020.
"[Luis] Suarez, look what they did to him," Jose Enrique continued. "You sign [Antoine] Griezmann who really is not even half of the player that Suarez is. That's what it is. So, they do a lot of strange things.
"They go out and buy [Ousmane] Dembele for 100 million. They do a lot of stuff. I remember when they signed [Philippe] Coutinho, and I love Coutinho. But they play him as a left winger as well. When actually, he's more a midfielder or number 10.
"So, they've been doing so many things wrong for many years, and now they are taking [the consequences]. They lose Messi, who obviously is the standout player of this club. He was, he’s not anymore.
"Now they are struggling, and I believe to get back to their best is gonna take a while. I don't know how long, depends on their spending, depends how much income they have, because obviously, they have to get rid of a lot of players.
"Again, for example, [Miralem] Pjanic. When they signed Pjanic, they [sent] away Arthur Melo and you're giving away the player that Messi actually says is the closest player he's seen to Xavi. And that he's 23, and you take Pjanic who is 30.
"It's a strange thing, and you have to say, "why are these things happening?"
"Obviously, I don't want to blame anyone, but I'm sure there's been things behind [the scenes] that are still being discovered.
"When the club is struggling it is because something is going wrong behind [the scenes], that’s reality. And that's why Barcelona is in the situation it is right now because they've been doing things wrong. Simple as that."