A hamstring injury to Liverpool's Trent Alexander-Arnold and fitness concerns over Chelsea's Reece James left the Three Lions with Luke Shaw as their sole fit full-back in the 25-man squad that was named on Friday.

Newcastle United's Kieran Trippier and Chelsea's Ben Chilwell are injured, while Kyle Walker of Manchester City was left out as Southgate considered his options. Manchester United man Shaw, while called up, has not played since the end of February after contracting coronavirus.

Southgate has reacted to the latest setbacks by calling in Southampton full-back Walker-Peters and Crystal Palace's Mitchell, who could make their senior debuts across friendlies against Switzerland and Ivory Coast.

Walker-Peters won the Under-20 World Cup in 2017, but Mitchell has not featured for any of England's youth sides.

Meanwhile, West Brom goalkeeper Sam Johnstone replaces Arsenal's Aaron Ramsdale, who missed Sunday's (AEDT) 1-0 win at Aston Villa with a muscle injury.

The final change saw Tammy Abraham, who scored twice in Roma's 3-0 derby win over Lazio on Monday, drop out as Aston Villa striker Ollie Watkins comes in.