Jurgen Klopp made nine changes to the XI that lost by the same scoreline to title rival Manchester City last Friday (AEDT) and it turned in a lethargic first-half display, trailing at the break to Raul Jimenez's opener.

Divock Origi found a fine equaliser but Portugal midfielder Neves raised the decibel levels significantly at Molineux with a decisive 55th-minute long ranger.

One of the players Klopp retained from the City defeat, Croatia centre-back Dejan Lovren, pulled up and had to be replaced in the sixth minute, meaning 16-year-old Dutch defender Ki-Jana Hoever became Liverpool's youngest player in FA Cup history

It was a couple of senior men who let their manager down in the 38th minute when Diogo Jota stole possession from James Milner and burst past Fabinho.

Jota played in Jimenez, who still had plenty to do but bore down on goal and steered an unerring finish beyond Simon Mignolet.

Liverpool pulled level six minutes into the second half when the hitherto anonymous Origi engineered a fraction of space on the edge of the box to smash home left footed.

Parity did not last long as Neves found an even better finish by launching a typically dipping and swerving effort from 30 yards.

Jimenez had the chance to move Wolves closer to round four when he picked Hoever's pocket but could not adjust his feet after going around Mignolet.

The run of spectacular second-half strikes continued as a sumptuous free-kick from Liverpool winger Xherdan Shaqiri hit the inside of the right post and somehow bounced to safety.

Klopp then called for the big guns, sending on Mohamed Salah and Roberto Firmino, but Wolves held on.