Jovic has been linked with LaLiga champion Barcelona, however, Spanish rival Madrid has reportedly emerged as favourite to sign the in-demand Eintracht star.
The 21 year-old Serbia striker has scored 25 goals in all competitions this season and his two-year loan from Benfica became permanent last week.
Amid the growing speculation over Jovic's future, Eintracht director Bobic told ZDF: "There's a real possibility that Jovic signs for Real Madrid.
"I hope and want him to stay here at Eintracht, but I'm also realistic and know that if a big club like Real Madrid want him then we haven't got a chance of keeping him."
Of Jovic's 25 goals, 17 of those have come in the Bundesliga as Eintracht sit fourth in the standings – the final Champions League qualifying spot.
Jovic's eight Europa League goals have also helped Eintracht reach the semi-finals, with Premier League side Chelsea awaiting in the last four.