Fury's camp had been adamant the fight would not go beyond the sixth round, and its man made good on those predictions in devastating fashion.
He controlled the opening five rounds with ease, demonstrating a gulf in reach and gulf in class between the fighters.
Whyte had struggled to make any kind of impression and his chance to do so in his maiden world title fight was taken away when Fury landed a crushing right uppercut.
The end result never looked in doubt, and the only question now is whether Fury will make good on his promise to end his career on the back of this victory.
Fury, returning to the United Kingdom after five fights in the United States, left the door open for another bout in the post-fight interview in which he suggested he would likely still walk away.
Yet he never opened the door for Whyte to take the WBC and lineal belts away from him.
Indeed, the only time Fury ever looked perturbed was during a tempestuous fourth round in which Mark Lyson had to repeatedly get involved, warning Whyte for following in with his head and Fury for hitting on the break.
The two fighters exchanged words and that episode perhaps increased Fury's desire to end things quickly, doing so with one of the finest punches of his professional career and perhaps his last.