Pete Horne starts at fly-half in one of four changes to the Scotland team to face France in the Six Nations on Saturday.
Gregor Townsend has turned to Horne in the absence of Finn Russell, who was ruled out with a head injury, so Adam Hastings has to settle for a place on the bench.
Blair Kinghorn is restored to the side in place of full-back Stuart Hogg (shoulder), while centre Nick Grigg replaces Huw Jones (knee) at Stade de France.
The other change is in the back row, with Magnus Bradbury handed a Six Nations debut after Ryan Wilson (knee) was ruled out.
Scotland head coach Townsend said: "Injuries create opportunities for others to show what they can do and, throughout the past couple of seasons, we've seen a number of players really step up.
"All of the players coming in started against Argentina in the summer, which ranks as one of our best-ever away performances.
"On top of that there is cohesion forged through familiarity at club level – Magnus in the back row lines up with club-mate Jamie Ritchie, and Pete Horne and Nick Grigg are either side of Sam Johnson in the backs."
Scotland: Blair Kinghorn, Tommy Seymour, Nick Grigg, Sam Johnson, Sean Maitland, Pete Horne, Greig Laidlaw (captain); Allan Dell, Stuart McInally, Simon Berghan, Grant Gilchrist, Jonny Gray, Magnus Bradbury, Jamie Ritchie, Josh Strauss.
Replacements: Fraser Brown, Alex Allan, Zander Fagerson, Ben Toolis, Gary Graham, Ali Price, Adam Hastings, Darcy Graham.