Belgium got their World Cup qualification campaign up and running as Kevin De Bruyne inspired them to a 3-1 comeback win over Wales.

In the first meeting of the teams since Wales' memorable 3-1 triumph in the Euro 2016 quarter-finals, the world's number one ranked side fell behind to Harry Wilson's 10th-minute opener.

Gareth Bale was central to Wales' opener, though Belgium's star player subsequently stepped up, levelling proceedings with a stunning effort.

Thorgan Hazard completed the turnaround six minutes later and, after a bright second-half performance from Wales, Roberto Martinez's team sealed a strong start to Group E through Romelu Lukaku's penalty.

Wales suffered a blow when Joe Allen hobbled off injured in the eighth minute, yet the visitors were celebrating a wonderfully worked goal moments later.

Bale was the heart of the 17-pass move, threading a perfect first-time throughball into the path of Wilson, who calmly slotted home.

De Bruyne's sensational right-wing cross handed Lukaku a golden chance to restore parity, only for the Inter forward to blaze over.

Wales' luck did not last, though, with De Bruyne taking full advantage of being given space and time 25 yards out – the Manchester City star's strike clipping in off the right-hand upright.

Wearing the number 10 shirt typically taken by his older brother Eden, Hazard got the assist for De Bruyne's equaliser, and the Borussia Dortmund playmaker turned scorer when he steered Thomas Meunier's cross home.

No stranger to magnificent overhead kicks, Bale could have equalised early in the second half, but failed to make full contact with an acrobatic attempt.

Lukaku saw a shot well blocked with 24 minutes remaining and De Bruyne sliced wide on the rebound.

But Wales' lingering hopes were quashed when Chris Mepham flung a boot at Dries Mertens and Lukaku drilled in from 12 yards to make sure of the victory.