Liverpool’s preparation for their highly anticipated Champions League showdown with Real Madrid has taken an unexpected hit. Alexander Isak, the club’s record signing, missed Monday’s training session at Anfield, sparking serious doubts about his availability for the crucial Matchday 4 group-stage encounter.

The Big Absence

Isak, who arrived for €150 million to lead Arne Slot’s new attacking project, has yet to fully recover from his muscle issues and now seems set to miss his fourth consecutive match. The Swedish striker has struggled to find consistency this season, managing just one goal and one assist in eight appearances before his setback.

His absence adds to Liverpool’s growing list of injuries, which already includes Alisson Becker and Jeremie Frimpong, both sidelined since late September. For Slot, who is under mounting pressure to revive the team’s form, losing Isak again is a major blow just as the Reds face their toughest European test yet.

A Midfield Boost for Arne Slot

Amid the concerns, there was at least one positive development: Curtis Jones returned to full training on Monday. The 24-year-old midfielder had missed the Carabao Cup tie against Crystal Palace and the recent Premier League win over Aston Villa, but his recovery comes at a crucial moment.

Slot hopes Jones’ return can bring stability and energy to a midfield that will be tested heavily by Real Madrid’s pressing and control. However, uncertainty remains in attack, with limited options available if Isak is officially ruled out.

Liverpool’s Uncertain Outlook

Liverpool’s recent form has been far from convincing — a patchy Premier League run combined with a Champions League defeat to Galatasaray has raised questions about Slot’s system and his squad’s confidence.

Isak’s continued absence not only weakens Liverpool’s attacking threat but also impacts the team psychologically. The club invested heavily in him as their long-term offensive leader, and the ongoing fitness struggles have disrupted both rhythm and chemistry.

The high-stakes clash between Liverpool and Real Madrid kicks off on Tuesday at 3:00 p.m. ET (12:00 p.m. PT) at Anfield, where the Reds will try to rediscover their identity and keep their European hopes alive.