The Serbian great is on his latest mission to win a record 25th Grand Slam title and dismissed the Italian 6-3, 6-2, 6-2.

Djokovic faces 75th-ranked Botic van de Zandschulp of the Netherlands next.

The former world number one, who won his first match by the same comprehensive scoreline, said: "Similar feeling on the court of generally positive."

The fourth seed did not play a warm-up tournament and said his longer off-season was paying off.

"I'm really happy I'm able to play this way, considering the lack of competitive matches for more than two months," the 38-year-old said.

"It's all been positive so far, positive signs."

In sunny, but noticeably cooler temperatures than recent days at Melbourne Park, Djokovic appeared determined to get the job done as fast as possible.

Playing in the early afternoon on Rod Laver Arena, rather than his usual evening slot, Djokovic raced into a 5-2 lead.

The Italian doggedly held serve despite facing multiple set points, but it was only delaying the inevitable as Djokovic sealed the opening set in 47 minutes.

Djokovic, who has been tied with Margaret Court on 24 major titles since winning the US Open in 2023, was not quite as devastating as when winning his first-round match by the same scoreline.

But he still had far too much for the outclassed 23-year-old.

Djokovic broke Maestrelli, who was making his Grand Slam debut, to start the second set and cantered into the third round.

Djokovic is well known for his sometimes unusual preparations, which include hugging a Brazilian fig tree in the nearby botanical gardens.

"That is my oldest friend here in Melbourne," said Djokovic, who has won 10 Australian Open titles, more than anyone in history.

"He has been there to heal my wounds and give me company.

"It's a beautiful connection, nature is such a powerful ally.

"We have a friendship going over 20 years."