Timothy Weah opened the scoring for the French visitors before Mbappe levelled from the spot and Madrid defender Dani Carvajal was sent off for headbutting Marseille goalkeeper Geronimo Rulli.

Roberto De Zerbi's enterprising Marseille were well place to push for a win until Facundo Medina was harshly penalised for a handball and Mbappe converted his second penalty.

Madrid coach Xabi Alonso was dealt an early blow on his first European game at the helm of the Spanish giants when Trent Alexander-Arnold limped off with a thigh injury.

Alonso benched Vinicius Junior among several changes to the side which beat Real Sociedad in La Liga on Saturday to continue Madrid's 100 percent start in La Liga.

They had a short pre-season following the Club World Cup, giving Alonso more incentive to shuffle his pack, while the coach has also insisted he will keep as many players involved as possible.

Jude Bellingham was named on the bench for the first time after undergoing shoulder surgery in July, but neither he nor the returning Eduardo Camavinga made it on to the pitch.

Mbappe, who watched former side Paris Saint-Germain win the Champions League last season after he left for Madrid, almost opened the scoring with a spectacular overhead effort which dropped just wide.

Alexander-Arnold limped off after just three minutes, to be replaced by veteran Carvajal.

Franco Mastantuono, Real Madrid's youngest Champions League starter at 18 years and 33 days, hit the inside of the near post as both teams sought to break the deadlock.

Rulli made a fine save from a fierce Mbappe strike before Weah opened the scoring. Mason Greenwood picked Arda Guler's pocket and fed the US international, who slammed past Thibaut Courtois at the near post for his first Marseille goal.

The Belgian goalkeeper denied Weah from distance as the Juventus winger, on loan in France, impressed. Real Madrid equalised when Geoffrey Kondogbia clumsily bundled over Rodrygo Goes in the box.

Mbappe, in fine form at the start of the season, dispatched the penalty past Rulli's outstretched arm.

Pierre-Emerick Aubameyang drilled just wide and then tested Courtois in the second half as Marseille continued to give as good as they got.

Madrid finished the second game running with 10 men after Carvajal squared off with Rulli and then pushed his head into the goalkeeper's.

However, just as they did against Real Sociedad after Dean Huijsen's red card, they finished with three points.

Medina slid in to challenge Vinicius and the ball hit his arm, with the referee awarding a penalty, which Mbappe gratefully dispatched to claim victory for Los Blancos.