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Leandro Trossard scored the decisive goal at Old Trafford with 20 minutes on the clock as Kai Havertz profited from an intercepted Andre Onana pass to tee up the Belgian's simple finish.

The Gunners moved one point clear of City, which thrashed Fulham 4-0 in its match and still has a game in hand at Arsenal's fierce rival Tottenham Hotspur on Wednesday (AEST), meaning the title remains in the hands of Pep Guardiola's side.

City then hosts West Ham United on the final day, while Arsenal is at home to Everton.

United, beaten 4-0 by Crystal Palace last week and now with just one win in its past eight in the competition, stays eighth on the table and is three points off Chelsea and Newcastle United directly above with a game to go.

Arsenal did not have any true sights of goal in an evenly contested opening, with United looking more coherent than in recent weeks, until the visitors' breakthrough arrived through Trossard.

Onana's pass was cut out on the halfway line and played to Havertz, who was kept onside by Casemiro failing to get up the pitch, and the German squared for Trossard to convert from point-blank range.

The Gunners, who failed to win on the two other previous occasions they had led at half-time at Old Trafford, were happy to sit back after the restart and invite United on to them.

Casemiro was invited to shoot from distance and did just that, forcing a save from David Raya, who then denied Antony's poor attempt from a similar position.

But there was to be no way through for United, which had Onana to thank for late saves to deny Gabriel Martinelli and Declan Rice, as the visitors completed a league double in this fixture for the first time since 2006-2007.

Trossard's goal, which came despite United having four players back in a position to intercept Havertz's pass, makes it 82 goals conceded for the Red Devils across all competitions this season – the most they have shipped in a single season since 1970-1971 (also 82).

Erik ten Hag's men were ultimately unable to hit back and have therefore now suffered 19 losses across all competitions this term, which is their most since 1977-1978 (also 19).

This is also just the third time in Premier League history United has lost at home to three sides from the capital in a single season, having previously fallen to Crystal Palace and Fulham.