The two teams had been set to meet in Vannes in the new tournament, a replacement for the scrapped autumn internationals due to the global pandemic.
Three days before the game, Fiji revealed two members of its travelling party had tested positive for COVID-19 and the contest was cancelled the next day when a further four cases affecting close contacts in the squad were reported.
"Whilst no fault has been apportioned to Fiji Rugby, the competition rules provide that if a team is primarily responsible for a match not taking place, a 28-0 victory will be awarded to the opposition that could have played the match," Six Nations Rugby, who are organising the competition, said in a statement.
"We wish the affected Fiji players well as they continue their recovery and are working closely with the Fiji team, to ensure that they are able to field a competitive team against Italy."
France will belatedly play their first match when they face Scotland at Murrayfield on Sunday.