Totti remains a key figure at the Stadio Olimpico, despite dropping out of Luciano Spalletti's starting XI, contributing six goals and four assists in his last 11 Serie A appearances stretching back to last season.
Expected to retire at the end of the current campaign, here are some of the startling numbers behind one of Italian football's all-time greats.
250 - A penalty against Torino on Monday (AEST) helped Totti score his 250th goal in Serie A. Only Silvio Piola (274) has more. No player has scored more goals for a single club in the league's history.
23 - Totti has scored in a record 23 consecutive Serie A seasons.
113 - A mind-blowing 26 per cent of the players to have played in Serie A in 2016-2017 (113 of 429) were not born when Totti made his league debut as a 16-year-old against Brescia on March 28 1993.
25 - This season is Totti's 25th in Italy's top flight, a tally matched only by another player to reach his 40s at the highest level, former AC Milan captain Paolo Maldini.
605 - Only two players (Maldini, 647 and Javier Zanetti, 615) have made more Serie A appearances than Totti's 605, although second place on that list is within the Roma captain's sights.
26 - Totti's most prolific campaign in front of goal was 2006-07. He was named Serie A top scorer with 26 strikes, adding six more in other competitions as Roma lifted the Coppa Italia.
38, 59 - A goal against CSKA Moscow in November 2014 made Totti the oldest scorer in Champions League history at 38 years and 59 days old.
5 - Totti was one of five players to play in every game of Italy's successful 2006 World Cup campaign. His four assists at the tournament was a tally bettered by nobody.
1 - Totti has just one Scudetto to his name, won in 2000-2001. He has been involved in eight second-place finishes since that triumph.
38 - No fewer than 38 Serie A opponents have felt the wrath of Totti and conceded a goal to the great man. A fellow 2006 World Cup winner trumps him, however. Alberto Gilardino has struck against 39 teams in Serie A.