Juan Cuadrado is optimistic about Juventus's chances of winning the Serie A again this campaign if it can replicate the form that saw it beat Manchester City 2-1 in Wednesday's (AEST) UEFA Champions League encounter.

The reigning champion has struggled so far in Serie A, but impressed with a fine outing at the Etihad Stadium as it saw off a City side which boasts a 100 per cent record in the Premier League.

"We'll be hard to stop if we play as we did last night," Cuadrado said.

"We put in a great performance and it was very important to cross the white line with the desire to get a result. When we play in that manner we're a truly great team.

"We played as a team, looking well organised and sticking to our game plan. In training we work to give our best, and that reaps rewards on matchday.

"After the game we said we need to believe in ourselves and that we're a strong side. Now it's time to bounce back in the league and defend our Scudetto title."

Juventus is 16th in Serie A with one point from three games.