It appeared set to be another disappointing game for under-fire Milan coach Gennaro Gattuso, who had seen the pressure eased slightly by three straight domestic victories, as Giovani Lo Celso's third goal in as many Europa League games put Betis on course for a second successive win over Milan having beaten them 2-1 at San Siro last time out.

However, a somewhat fortuitous 62nd-minute free-kick from Suso levelled matters after Betis wasted chances to extend their lead.

The mood at Estadio Benito Villamarin was dampened significantly eight minutes from time when Milan defender Musacchio was taken off on a stretcher in a neck brace after clashing heads with team-mate Franck Kessie.

Betis opened the scoring in fine fashion in the 12th minute. Neat interplay between William Carvalho and Joaquin fed Junior Firpo down the left and his excellent pull back was confidently tucked into the bottom-right corner by Lo Celso.

Lo Celso and Joaquin then combined in a one-two that sent the latter through down the left side of the box, the veteran prodding towards goal but seeing his effort cleared by Ricardo Rodriguez to prevent Betis doubling their lead.

Again Lo Celso was involved as another clear-cut chance to make it 2-0 went begging, the midfielder playing the ball into Joaquin after a surging run before a low cross from Firpo was stabbed wide by Antonio Sanabria.

Milan came to life somewhat after the restart and an acrobatic save from Pau Lopez was required to keep out a curling effort from Suso.

But Lopez was unsighted as Suso restored parity three minutes later, his inswinging free-kick drifting beyond everyone in the box and into the bottom-left corner.

Fabio Borini then forced Lopez into action once more with a strike off the outside of his boot but the game ended on a concerning note as Musacchio left the field to applause from the entire stadium.