England was unable to complete another late rescue act as its 18-match winning streak was halted by Ireland in Dublin, along with dreams of a Six Nations Gland Slam.
RBS Six Nations: Ireland 13-9 England
Ireland battled to a deserved 13-9 victory in Dublin to deny England a second successive Six Nations Grand Slam and bring an end to the record-equalling winning run of Eddie Jones's men.
England matched New Zealand's mark of 18 consecutive victories by a tier-one Test nation last weekend as it wrapped up the championship title by trouncing Scotland.
However, just like the All Blacks in Chicago last year, England saw its lengthy streak halted by Ireland, which had much the better of a scrappy opening period before holding off a predictable response from its visitor in the second half.
An injury-hit Ireland led 10-3 at the interval, Iain Henderson's converted try the least its dominance of possession and territory merited.
Points all came from the boots of Ireland's Jonathan Sexton and England's Owen Farrell thereafter, the visitors unable to assert any dominance in the match as Ireland maintained its rage from start to finish to upset the champion.
England has made a habit of finishing games strongly under Jones, but an improved display after the break was not enough to prevent the Australian overseeing a first defeat since he succeeded Stuart Lancaster in the wake of a dismal 2015 Rugby World Cup campaign.