Naomi Osaka's promising Italian Open run was halted by Zheng Qinwen on Monday, as the seventh seed denied the four-time grand slam champion a quarter-final place.

Following Saturday's triumph over Daria Kasatkina – her second successive straight-sets win over a top-20 opponent in Rome – Osaka laughed off the "Clayomi" moniker given to her by some fans.

On Monday, her old troubles on the surface came back to the fore as Zheng dominated from the off to make the tournament's last eight for a second straight year, winning 6-2 6-4.

Osaka saw her serve broken in the very first game only to hit straight back, but Zheng assumed control by taking seven straight games to go from 2-1 down in the opener to 2-0 up in the second set.

The 21-year-old produced a clinical performance and converted all four of her break points, winning 78 per cent of first-serve points to Osaka's 68 per cent as she teed up a quarter-final clash with either Coco Gauff or Paula Badosa.

Data Debrief: 'Clayomi' no more as Zheng triumphs

Osaka impressed on a surface long regarded as her worst in Italy, but it was a bridge too far for her on Monday, Zheng reaching her fourth WTA 1000 quarter-final.

Since the format's introduction in 2009, she is just the second Asian player to reach multiple quarter-finals on both hardcourts and clay at that level before the age of 23, the other being Osaka.