Manchester United striker Rasmus Hojlund is due to miss next weekend’s derby against Manchester City after suffering a muscle injury in a significant blow for manager Erik ten Hag.

The in-form 21-year-old, who had scored seven goals in his last six appearances for United, will sit out Saturday’s Premier League match against Fulham and Wednesday’s FA Cup fifth-round tie at Nottingham Forest.

United said the Denmark international is expected to miss two to three weeks, a timeframe that would also rule him out of the trip to the Etihad Stadium a week on Sunday.

“It’s a small injury, two to three weeks,” Ten Hag said in Friday’s press conference. “That’s what happened, that is the risk playing high intensity, training. It’s not a big injury but he has to wait now for two, three weeks.”

Hojlund’s injury – which comes in the same week that Luke Shaw was ruled out for several months – leaves Ten Hag short of options in attack with Anthony Martial already sidelined until April following a groin operation and it is likely that Marcus Rashford will be asked to play in a central role.

Ten Hag was speaking for the first time since Sir Jim Ratcliffe’s purchase of a minority stake in the club was ratified and after the billionaire gave a wide-ranging interview in midweek in which he laid out ambitious plans to knock the likes of Manchester City and Liverpool “off their perch”.

Ten Hag said he and Ratcliffe, whose Ineos group have taken control of footballing operations following the deal, are on the same page.

“We speak a lot, we have many conversations with him and with Dave Brailsford (Ineos director of sport) about this club, about the team about the structures,” he said. “We are very aligned. Their ambitions fit with the ambitions I have, with the ambitions I had when I came in.

“We are in that project now. For me, I’m 18, 19 months in and I see (things) go in the right direction. We had setbacks in the second season but you see the team coming, you see the squad progressing and developing.”

And the Dutchman denied that he would find himself under increased pressure given the expectations that Ratcliffe will have for the club. United have won four in a row in the league but remain five points adrift of the top four.

“No more pressure because we have the same ambition, we have the same targets,” Ten Hag said. “I see the process and I see this team is developing, it’s progressing.

“I see we have now also the right age across the squad, we can make that even stronger and they will grow and we will do everything in our power. There is strong competition and there are reasons behind it.

“We still have to catch up in the moment where every game is a final for us because we have to be in the Champions League. The players want this, the team want this but we have to believe.”

Injuries, however, could be the thing that derails United’s bid to break into the top four.

Hojlund and Shaw have joined an injury list that already includes Martial, Aaron Wan-Bissaka, Lisandro Martinez, Mason Mount and Tyrell Malacia.

“Of course that is an issue but other clubs have this and we have to deal with this,” Ten Hag said. “I feel we can deal with it better but still it’s an issue with the depth of the squad, and the squad have to prove it.”