The Belgium international, who joined Madrid from Chelsea in June, has only recently returned to training following a thigh injury and made his debut in Saturday's LaLiga victory over Levante as a second-half substitute.
The Spanish giants kick off their campaign to win a 14th Champions League title at PSG and Zidane is confident Hazard will feature from the start.
"You will see how we're going to play tomorrow, but Hazard is ready to play and ready to start," he told a media conference. "We've had some good training sessions recently and he's ready."
Zidane was quick to praise French striker Karim Benzema following PSG boss Thomas Tuchel's assertion that he is "fantastic and undervalued".
"It hasn't been easy for him but he's always showed the kind of player he is," he added. "He's a goalscorer but that's not the most important thing in football.
"He's a team player and that's what I like the most. I think he's fantastic, just like Tuchel said. I think the same way."
James Rodriguez played the full 90 minutes of the weekend win over Levante, teeing up Benzema for Los Blancos' second goal.
Zidane would not be drawn on whether he would start against the Ligue 1 champions, but he did praise the Colombia international's versatility.
"We'll see, because he can play everywhere, but it's true that it is easier for him to play up front," he said. "It's important for him to be in good form and he is. His position on the field can change because he is a quality player."
Madrid and PSG are red-hot favourites to progress from Group A, which also includes Club Brugge and Galatasaray, with Zidane suggesting the French champions have enough quality to go all the way.
"PSG is also a favourite in the Champions League because they are a great team," he said. "They are always dangerous although sometimes they do not get the expected results.
"But it is a team that is dangerous, which they show every weekend. With [Edinson] Cavani, [Kylian] Mbappe and Neymar they are better, but they are a team that is at a very high level even without those three."