Aleksandar Mitrovic again denied Wales victory as Chris Coleman's men were held to a fifth consecutive draw in World Cup qualifying after their match in Serbia on Sunday ended 1-1.
Wales have not reached a World Cup since 1958 and they remain four points shy of their opponents at the Group D summit after goals from Aaron Ramsey and Mitrovic.
Although Wales' winless run goes on without suspended star man Gareth Bale, they will surely ruefully reflect on the opportunities passed up in four consecutive draws prior to visiting Belgrade - rather than a hard-fought point here - if they fail to close the gap to Serbia.
The unwanted streak includes a draw secured by Mitrovic's late header for Serbia in Cardiff in November.
The hosts' unbeaten record against Wales was threatened again by Arsenal star Ramsey's nonchalant first-half penalty.
But, once more, Mitrovic proved their nemesis with a clinical left-footed strike - a fifth of the campaign - to move his side back above Republic of Ireland, who also have 12 points, on goal difference at the top of the table.