Uruguay international Cavani has proved a popular addition to Ole Gunnar Solskjaer's squad this term, scoring seven goals and supplying two assists across 25 appearances in all competitions.
Solskjaer recently said an extended stay at Old Trafford was possible for the 34-year-old, but Cavani's father Luis told TyC Sports that a return to South America could be on the cards.
"My son is not happy in England and wants to return nearer his family. He wants to play in South America.
Luis Cavani, Papá de Edison: "Hay un 60 por ciento de chances que mi hijo vuelva a Sudamérica. Habla siempre con Riquelme y me encantaria que haga dupla con Tevez" pic.twitter.com/JxiSJafkhd— Superfútbol (@superfutbol) March 9, 2021
"I want Edinson to play for a team which fights for important trophies. He has had many conversations with [Boca vice-president Juan Roman] Riquelme and would like to play for Boca.
"At the halfway point of the year, he'd like to return to South America. My son’s idea is not to continue there [in Manchester]. He wants to return.
"I think he's going to come back in June this year."
Cavani Sr cited his son's punishment by the Football Association for using a racially insensitive word in a social media post as a factor in his unhappiness.
Cavani was handed a three-game ban for bringing the game into disrepute by the Football Association (FA), although CONMEBOL and the Uruguayan FA came out in defence of the player.
"There are things which sometimes annoy us as humans, as people. The whole ban issue annoyed him," Luis Cavani added.
"That has been playing on him, sometimes players can't find form either. These things can weigh heavy on you. Sometimes mentally you can get dragged down."
It remains to be seen what impact this development has upon Cavani's future, with Solskjaer having previously stated United were open to taking up an option of a further 12 months with the former Paris Saint-Germain and Napoli star.
"I can only say Edinson has done well," the United manager said. "I've been impressed by him, he's really gelled in the group and we’ll sit down and speak with him in the near future to see his plans and our plans.
"It's a good discussion to have. We always speak to the players, and with his contract situation at the moment we’re very pleased with what he’s done."