Antetokounmpo's double-double of 36 points and 15 rebounds helped the Bucks past the Boston Celtics 119-112.
The reigning NBA MVP went 14-of-20 from the field in the Bucks' victory.
Marcus Smart scored 23 points off the bench for Boston, while Jaylen Brown contributed 22 points.
James Harden starred with 49 points in the Rockets' 153-149 overtime win against the Dallas Mavericks.
Kristaps Porzingis (39 points and 16 rebounds) led the Mavericks, but they fell short.
Fantastic Fournier, Portland trio shine
Jayson Tatum struggled badly in the Celtics' loss. The forward went two-of-18 from the field for just five points in 32 minutes.
Harden's hot start
Harden made a fast start with 23 points in the first quarter for the Rockets.
Orlando Magic 128-118 Brooklyn Nets
Portland Trail Blazers 140-135 Memphis Grizzlies
Phoenix Suns 125-112 Washington Wizards
Milwaukee Bucks 119-112 Boston Celtics
San Antonio Spurs 129-120 Sacramento Kings
Houston Rockets 153-149 Dallas Mavericks
Lakers face Raptors