James' triple-double of 34 points, 13 assists and 12 rebounds helped the Lakers bounce back from their loss to the Memphis Grizzlies with a 122-114 victory over the Pelicans.
Zion Williamson, the top pick in the 2019 NBA Draft, delivered one of the best performances of his young career with a career-high 35 points and seven rebounds.
Without Anthony Davis (knee), the Lakers had six players finish with double-digits in points, including Kyle Kuzma (20).
Antetokounmpo powered the high-flying Milwaukee Bucks past the Charlotte Hornets 93-85.
The 2019 NBA MVP finished with 41 points, 20 rebounds and six assists as the Bucks improved to 52-8.
Leonard lifts Clippers, Jokic shines
Kawhi Leonard's 30 points helped the Los Angeles Clippers to a 136-130 win over the Philadelphia 76ers. Shake Milton had a game-high 39 points for the 76ers in the absence of Joel Embiid, Ben Simmons and Josh Richardson.
Nikola Jokic's triple-double of 23 points, 18 rebounds and 11 assists guided the Denver Nuggets past defending champions the Toronto Raptors 133-118.
The Dallas Mavericks crushed the Minnesota Timberwolves 111-91 as Kristaps Porzingis contributed 38 points and 13 rebounds.
Bad Bridges, Biyombo
Miles Bridges (seven points in 35 minutes) and Bismack Biyombo (eight points in 22 minutes) combined to go five-of-21 from the field in the Hornets' loss.
LeBron, Zion put on a show
James and Williamson thrilled during the Lakers' win over the Pelicans.
Milwaukee Bucks 93-85 Charlotte Hornets
Dallas Mavericks 111-91 Minnesota Timberwolves
Los Angeles Clippers 136-130 Philadelphia 76ers
Denver Nuggets 133-118 Toronto Raptors
Sacramento Kings 106-100 Detroit Pistons
Los Angeles Lakers 122-114 New Orleans Pelicans
Washington Wizards 124-110 Golden State Warriors
Bucks at Heat
The Bucks (52-8) will aim for a seventh straight win when they face the Heat (38-22) in Miami on Monday.