The veteran forward is expected to join the Trail Blazers ahead of their road match-up with the New Orleans Pelicans on Tuesday.
Anthony, 35, has been out of the league since he was waived by the Chicago Bulls back in February and last played a game in November 2018 for the Houston Rockets.
The 10-time All-Star is determined to grasp his opportunity now he has secured his return.
The veteran forward said in a YouTube clip: "I always kept my eye on Portland. It just didn't work out at other times. But now it seems like a perfect opportunity.
"I just look at that team and say, 'This is what I can bring, this is where I can help'. It can only work if all parties see it the same way.
"What happened before is the past; I can't dwell on that. I learned from that.
"This happened at a point of time in my life where I do have a lot of clarity and understanding of different situations, just life. My approach is totally different."
Portland made the Western Conference Finals last season but are struggling at 5-9 this time around and lost 132-108 to the Rockets on Monday.