The England international heads to Spain in the hope of reinvigorating his career, which stagnated in the aftermath of the World Cup in 2018.
Right-back Trippier exceeded expectations in Russia, scoring the opening goal in the semi-final defeat to Croatia, but lost form on his return to Tottenham.
📝 | Agreement with @SpursOfficial over the transfer of @trippier2.— Atlético de Madrid (@atletienglish) July 17, 2019
🏴 The Englishman has signed a three-year contract 😀
👋 Welcome to the Atleti Family! 🔴⚪🔴
👉 https://t.co/Wg399LgNOg#WelcomeTrippier #AúpaAtleti pic.twitter.com/wATXjFnCbb
Serie A side Napoli expressed firm interest despite the 28-year-old slipping out of the England squad, while Juventus and Manchester United were also linked.
Atleti ultimately outlasted their competitors to secure a direct replacement for the long-serving Juanfran, who left on a free at the end of June.
Santiago Arias and the injured Sime Vrsaljko are the other right-backs on the free-spending LaLiga club's books.
Trippier's departure leaves Spurs boss Mauricio Pochettino to choose from Serge Aurier, Kyle Walker-Peters and Juan Foyth on the right side of defence.