La Roja have won three and drawn three of their six matches since experienced coach Lasarte replaced Reinaldo Rueda in February.
Chile are assured of a place in the knockout stages, but Lasarte is eager to avoid going through in fourth place, which would mean a quarter-final tie with favorites Brazil.
"We do not want to qualify in last place. Avoiding Brazil is key as they are the most powerful side in the tournament," he said.
"The draw against Uruguay, who have a lot of great players, was not bad. I'd have liked a win, but to draw was good."
Paraguay still have work to do if they are to progress out of the group, having followed up a 3-1 win over Bolivia in their first game with a 1-0 loss to Argentina last time out.
Papu Gomez scored the only goal of the game after 10 minutes for Argentina and Paraguay could not find a leveller, despite having more of the ball.
Los Guaranies will now be looking to overcome Chile in order to stay in the hunt for a top-four spot that would see them advance.
Head coach Eduardo Berizzo said: "We played a solid game defensively against Argentina and we have to continue with that.
"The attitude has been very good from the team and the players have given everything. We weren't rewarded for our efforts in the last game but we will try again."
PLAYERS TO WATCH
Chile – Claudio Bravo
The Real Betis goalkeeper is the oldest player taking part in the Copa America at 38 years, but he is showing that age is just a number.
He has made the most saves among keepers to have played at least two games with 11 in total across three appearances (3.7 per game on average).
Paraguay – Alejandro Romero Gamarra
Gamarra has only played twice so far in this year's Copa America, yet he has created more chances than any other player in the competition (12) prior to Wednesday's games.
The prolific Al-Taawoun attacker was also on target in his side's victory over Bolivia to make it four goals in eight senior caps for Paraguay.
KEY OPTA FACTS
– Paraguay are unbeaten in their last four games against Chile on neutral soil (W2 D2).
– Chile have not conceded more than one goal in any of their six games under head coach Lasarte.
– Paraguay have the highest possession in this year's Copa America (66.8 per cent) and have created 16.5 chances per game, more than any other side.