Brazil beat Peru in the 2019 Copa America final and will be hoping history repeats itself as they aim to make it two wins from two games.
Edwin Cardona capped a stunning team move as Colombia avenged their 6-1 loss to South American rivals Ecuador.
Argentina and Lionel Messi begin their Copa America campaign against Chile, the team who beat them on penalties in the 2015 and 2016 finals.
With familiar faces in the squad, Paraguay are eyeing their first trophy since 1979.
Lionel Scaloni made a late change to his roster for the Copa America, as Argentina target a first continental title since 1993.
Luis Muriel is not taking Venezuela lightly as Colombia aim to take another step towards qualification for the Copa America knockouts.