Lionel Messi was subdued in San Juan, where Argentina and Brazil played out a stalemate on Tuesday.
Angel Di Maria was the difference away to rivals Uruguay, his seventh-minute strike lifting Argentina to victory on Friday.
Argentina had led 2-0 inside eight minutes but conceded deep into stoppage-time in their 2022 World Cup qualifier in Colombia.
Brazil have named a 24-man squad for games against Ecuador and Paraguay, with Manchester United midfielder Fred among those included.
The South American confederation has announced that the first World Cup qualifiers of the year will be played in June.
CONMEBOL announced the suspension of March World Cup qualifiers due to coronavirus restrictions
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