A brace from Santi Cazorla halted Real Madrid's momentum as Luis Garcia's side claimed a 2-2 draw in the first LaLiga match of 2019.
Jose Antonio Reyes is back playing in Spain following a brief spell in China, joining Extremadura in their relegation battle.
Barcelona coach Ernesto Valverde has afforded Lionel Messi a rest for the Copa del Rey contest away to Sevilla on Wednesday.
Kevin-Prince Boateng's move to Barcelona surprised many, but Ernesto Valverde pointed to his track record in the transfer market.
Koke sustained a thigh problem against Huesca on Saturday, but Atletico Madrid understand it is not serious.
Kevin-Prince Boateng has spoken highly of Real Madrid and Cristiano Ronaldo before, but he backtracked in his Barcelona unveiling.