US Open champion Bianca Andreescu has withdrawn from the Tokyo Open due to a right leg injury.
Andreescu claimed her maiden grand slam title with a victory over Serena Williams last Saturday.
The teenager will not feature in Osaka next week, though, as her exploits at Flushing Meadows have taken a toll.
"I'm sorry to have to miss The Toray Pan Pacific Open this year," the 19-year-old said. "I know It's the biggest women’s tennis event in Japan and one that I look forward to playing in in the future. Hope to see you all soon!"
Belinda Bencic also misses out following her run to the last four in New York - where she was beaten by Andreescu - due to a foot injury.
French Open finalist Marketa Vondrousova is another player who will start the Asian swing later than planned, as she is struggling with a wrist injury.